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Quadrant -I (Video)

Purine Degradation Pathway

Degradation of dietary nucleic acids occurs in the small intestine, where a family of pancreatic enzymes hydrolyzes the nucleic acids to nucleotides. Inside the intestinal mucosal cells, purine nucleotides are …

Quadrant - II (Study Material)

1. purine degradation pathway

2. PURINE DEGRADATION

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Quadrant - III (Assignments)

1. PURINE DEGRADATION

INTRODUCTION: Purine Degradation refers to a regulated series of reaction by which human purine Ribonucleotides and Deoxyribonucleotides are degraded to Uric acid [end products] in humans & then excreated by the body. Purine = Adenine and Guanine Purine is a heterocyclic aromatic organic compound that consist of two rings pyrimidine and imidazole fused together.

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Quadrant - IV (MCQs)

1. ------ is the end product of purine metabolism in humans

3. Synthesis of urea occurs in ---------

4. Which of the following would NOT be expected to contribute to hyperuricemia (gout)

5. Allopurinol is an inhibitor of xanthine oxidase. Administration of allopurinol to a patient with gout and normal HG-PRT levels …

6. Which of the following are included in purine nucleotide

7. Addition of CO2 produces which compound in purine synthesis pathway

8. Synthesis of purine nucleotide can be done through how many process

9. Mechanism of action of allopurinol is----- a) Recombinant Uricase b) Decrese chemotaxis c) Xanthine oxidase inhibition d) Increase uric …

10. Which of the following increases uric acid excretion

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