KVV E-Modules - Glycolysis

Quadrant -I (Video)

Glycolysis

Glycolysis is the metabolic pathway that converts glucose (C6H12O6) into pyruvate and, in most organisms, occurs in the liquid part of cells (the cytosol). The free energy released in this …

Quadrant - II (Study Material)

1. Glycolysis

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Quadrant - III (Assignments)

1. Glycolysis

Glycolysis is the process by which one molecule of glucose is converted into two molecules of pyruvate, two hydrogen ions and two molecules of water. This leads to the synthesis of the ‘high energy’ intermediate molecules of ATP and NADH. Pyruvate molecules then proceed to the link reaction, where acetyl-CoA is produced and acetyl-CoA then proceeds to the TCA cycle. In this article, we will look at the steps of glycolysis, and its regulation and consider some clinical conditions related to glycolysis.

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Quadrant - IV (MCQs)

1. -------- enzyme in glycolysis not catalyzes an irreversible reaction

A: ) Hexokinase B: b) Phosphofructokinase C: c) Pyruvate kinase D: d) Pyruvate dehydrogenase

2. A single molecule of glucose generates _________ molecules of acetyl CoA, which enters the Krebs cycle.

A: a) 4 B: b) 3 C: c) 2 D: d) 1

3. ------hormones are primarily responsible for lowering blood glucose levels by promoting glucose uptake into cells

A: a) Insulin B: b) Glucagon C: c) Epinephrine D: d) Cortisol

4. The EMP pathway in eukaryotes usually takes place in-------

A: a) nucleus B: b) lysosome C: c) Golgi apparatus D: d) cytosol

5. In EMP pathway, the process by which ATP is formed from ADP is--------

A: a) reduction B: b) oxidative phosphorylation C: c) substrate-level phosphorylation D: d) photo phosphorylation

6. Cleavage of Fructose 1, 6-biophosphate yields ___________

A: a) Two aldoses B: b) Two ketoses C: c) An aldose and a ketose D: d) Only a ketose

7. ---------------- is the first step in the payoff phase of glycolysis

A: a) Reduction of 1, 3-bisphosphoglycerate to glyceraldehyde 3-phosphate B: b) Oxidation of glyceraldehyde 3-phosphate to 1, 3-bisphosphoglycerate C: c) Reversible conversion of dihydroxyacetone phosphate to glyceraldehyde 3-phosphate D: d) Irreversible conversion of dihydroxyacetone phosphate to glyceraldehyde 3-phosphate

8. High concentration of glucose 6-phosphate is inhibitory to ___________

A: a) Hexokinase B: b) Pyruvate kinase C: c) Glucokinase D: d) Phosphofructokinase-1

9. ------- is an enzyme that is common in both Glycolysis and Gluconeogeesis

A: a) Glucokinase B: b) Phosphofructokinase 1 C: c) Aldolase D: d) Fructose bisphosphatase

10. Under anaerobic conditions, the end product of glycolysis is converted to-------

A: a) CO2 and H2O B: b) Amino Acids C: c) Lactic acids D: d) HCl

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