KVV E-Modules

1. What is solubility?

A: A. Ability of a substance to evaporate B: B. Ability of a solute to dissolve in a solvent at a specific temperature C: C. Ability of a solvent to change color D: D. Ability of a drug to crystallize

2. Which factor can affect the solubility of a drug?

A: Temperature B: pH C: Nature of solute and solvent D: All of the above

3. The method commonly used to determine drug solubility in the laboratory is:

A: Distillation method B: Shake flask method C: Filtration method D: Centrifugation method

4. Intrinsic solubility refers to:

A: Solubility of an ionized drug B: Solubility of a drug at any pH C: Solubility of the unionized form of a drug D: Solubility of a drug in organic solvent

5. According to the Biopharmaceutics Classification System (BCS), drugs with low solubility and low permeability belong to:

A: Class I B: Class II C: Class III D: Class IV