KVV E-Modules - Abuse of Drug

Quadrant -I (Video)

Introduction to Drug Abuse- Dr. Hemanthkumar R.G

Classification and Examples of Commonly Abused Drugs- Dr. Sujata Abhay Jadhav

Pathophysiology and Mechanism of Addiction- Dr. Anjali Ravindra Shinde

Clinical Features and Diagnosis of Substance Use Disorders-Dr. Siddhant Mahapatra

Management of Drug Abuse- Intoxication - Dr. Ajish Gopinath Mangot

Management of Drug Abuse- Withdrawal- Dr. Ajish Gopinath Mangot

Legal and Ethical Aspects of Drug Abuse- Dr. Hemanthkumar R.G

Role of Medical Students & Professionals in Prevention of Drug Abuse -Dr. Sujata Vaijaysinh Patil

Quadrant - II (Study Material)

1. Introduction to Drug Abuse- Dr. Hemanthkumar R.G

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2. Classification and Examples of Commonly Abused Drugs- Dr. Sujata Abhay Jadhav

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3. Pathophysiology and Mechanism of Addiction - Dr. Anjali Ravindra Shinde

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4. Clinical Features and Diagnosis of Substance Use Disorders- Dr. Siddhant Mahapatra

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5. Management of Drug Abuse- Intoxication- Dr. Ajish Gopinath Mangot

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6. Management of Drug Abuse- Withdrawal- Dr. Ajish Gopinath Mangot

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7. Legal and Ethical Aspects of Drug Abuse- Dr. Hemanthkumar R.G

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8. Role of Medical Students & Professionals in Prevention of Drug Abuse - Dr. Sujata Vaijaysinh Patil

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Quadrant - III (Assignments)

1. Introduction to Drug Abuse- Dr. Hemanthkumar R.G

Introduction to Drug Abuse- Dr. Hemanthkumar R.G

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2. Classification and Examples of Commonly Abused Drugs- Dr. Sujata Abhay Jadhav

Classification and Examples of Commonly Abused Drugs- Dr. Sujata Abhay Jadhav

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3. Pathophysiology and Mechanism of Addiction - Dr. Anjali Ravindra Shinde

Pathophysiology and Mechanism of Addiction - Dr. Anjali Ravindra Shinde

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4. Clinical Features and Diagnosis of Substance Use Disorders- Dr. Siddhant Mahapatra

Clinical Features and Diagnosis of Substance Use Disorders- Dr. Siddhant Mahapatra

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5. Management of Drug Abuse- Intoxication - Dr. Ajish Gopinath Mangot

Management of Drug Abuse- Intoxication - Dr. Ajish Gopinath Mangot

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6. Management of Drug Abuse- Withdrawal- Dr. Ajish Gopinath Mangot

Management of Drug Abuse- Withdrawal- Dr. Ajish Gopinath Mangot

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7. Legal and Ethical Aspects of Drug Abuse- Dr. Hemanthkumar R.G

Legal and Ethical Aspects of Drug Abuse- Dr. Hemanthkumar R.G

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8. Role of Medical Students & Professionals in Prevention of Drug Abuse - Dr. Sujata Vaijaysinh Patil

Role of Medical Students & Professionals in Prevention of Drug Abuse - Dr. Sujata Vaijaysinh Patil

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Quadrant - IV (MCQs)

Drug use is best defined as:

A: Taking drugs to relieve stress B: Taking drugs without prescription C: Taking drugs as prescribed for a valid medical reason D: Using drugs to improve performance

Which of the following is an example of drug misuse?

A: Taking morphine for severe pain as prescribed B: Using antibiotics for viral fever without prescription C: Drinking alcohol occasionally D: Using insulin for diabetes

Drug abuse refers to:

A: Accidental overdose B: Use of drugs only in hospitals C: Use of substances for pleasure or to escape stress D: Long-term prescribed drug therapy

Drug dependence is characterized by:

A: Occasional use of drugs B: Psychological or physical reliance with withdrawal symptoms C: Use of drugs only during exams D: Legal prescription use

Which factor increases vulnerability to drug abuse among medical students?

A: Limited academic workload B: Easy access to prescription drugs C: Short study hours D: Strong peer supervision

According to the session, the earliest stage of drug abuse often begins with:

A: Criminal behavior B: Hospital admission C: Small, seemingly harmless use D: Legal action

Which of the following is a common myth about drug abuse?

A: Addiction alters brain function B: Anyone can develop addiction C: Prescription drugs are always safe D: Early intervention helps recovery

Which substance group is commonly abused in India, as mentioned?

A: Antibiotics only B: Vaccines C: Cannabis, opioids, alcohol D: Antacids

One major professional consequence of drug abuse for medical students is:

A: Improved academic performance B: Increased social acceptance C: Risk to future medical practice D: Better stress management

The most effective first step in preventing drug abuse is:

A: Punishment B: Ignoring early signs C: Awareness and early help-seeking D: Awareness and early help-seeking

Following are the drugs of abuse EXCEPT

A: Heroin B: Aspirin C: Cocaine D: Ketamine

Heroin is a commonly abused opioid that is illegally sold in which form?

A: Liquid Syrup B: Powder C: Tablet D: Patch

Benzodiazepines are most commonly prescribed for the treatment of:

A: Antianxiety and Insomnia B: Severe Pain C: Depression only D: Bacterial infections

Which of the following drugs is classified as a Psychostimulant?

A: Alcohol B: Morphine C: Cocaine D: Diazepam

Which of the following is the most commonly used depressant?

A: Barbiturates B: Alcohol C: Opioids D: Cannabis

What is addiction primarily categorized as?

A: A psychological disorder B: A neurological disorder affecting the brain's reward system C: A physical illness D: A behavioral problem

Which brain pathway is central to addiction due to its role in dopamine release?

A: Corticospinal pathway B: Spinothalamic tract C: Mesolimbic dopamine pathway D: Reticulospinal pathway

Which neurotransmitter plays a key role in the brain reward pathway involved in addiction?

A: Dopamine B: Acetylcholine C: Norepinephrine D: Histamine

Tolerance to a drug is best described as:

A: Increased effectiveness of a drug over time B: Reduced effectiveness requiring higher doses for the same effect C: Withdrawal symptoms when drug use is stopped D: Psychological craving only

Pharmacokinetic tolerance is caused by:

A: Receptor desensitization B: Enzyme induction or inhibition affecting drug metabolism C: Increased receptor sensitivity D: Genetic mutations

Which of these drugs commonly cause enzyme induction leading to pharmacokinetic tolerance

A: Barbiturates, phenytoin, rifampicin B: Benzodiazepines, opioids C: Cocaine, amphetamines D: Antidepressants

Physical dependence on a drug is characterized by:

A: Intense physical symptoms upon withdrawal B: Psychological craving only C: Occasional use without symptoms D: Increased tolerance but no withdrawal symptoms

Neuroadaptation in opioid dependence involves:

A: Increased dopamine release during withdrawal B: Receptor internalization and desensitization C: Increased postsynaptic receptor activation D: Decreased GABA release during withdrawal

Chronic alcohol use affects neurotransmitter systems by:

A: Enhancing NMDA receptor activity B: Downregulating GABA-A receptors and upregulating NMDA receptors C: Suppressing glutamate receptors permanently D: Increasing serotonin receptor sensitivity

A man with alcohol dependence reports that earlier he felt intoxicated after 2 drinks, but now needs 6–7 drinks to …

A: Withdrawal B: Craving C: Tolerance D: Protracted withdrawal

A chronic alcohol user develops sweating, tremors, anxiety, and insomnia 24 hours after stopping alcohol. According to DSM-5, how many …

A: One B: Two or more C: Three or more D: Five or more

A patient abstinent from alcohol for 2 months continues to complain of anxiety, insomnia, and mild autonomic symptoms. This phase …

A: Acute intoxication B: Delirium tremens C: Protracted withdrawal D: Complicated withdrawal

Which component of cannabis is primarily responsible for its psychoactive effects in the CNS?

A: Delta-11 THC B: Delta-9 THC C: Cannabidiol D: Anandamide

A postgraduate trainee denies excess drinking but has repeated minor accidents, becomes irritable after evenings out, and often uses alcohol …

A: Academic stress B: Denial or minimization of drinking C: Poor sleep hygiene D: Introverted personality

Which of the following is a presenting feature of alcohol intoxication?

A: Pupillary constriction B: Slurred speech C: Hyperreflexia D: Bradycardia

The most life-threatening complication in opioid intoxication is:

A: Agitation B: Vomiting C: Respiratory depression D: Tachycardia

The initial dose of naloxone in opioid intoxication is:

A: 10 mg IV stat B: 0.4–2 mg IV every 2–3 minutes C: 5 mg IM once D: 0.01 mg/kg IV once

In opioid-tolerant patients, naloxone should be started at:

A: 2 mg B: 1 mg C: 0.4 mg D: 0.04–0.1 mg

Pupillary constriction is commonly seen in:

A: Alcohol intoxication B: Cannabis intoxication C: Opioid intoxication D: Benzodiazepine intoxication

Which condition is a differential diagnosis of alcohol intoxication?

A: Bronchial asthma B: Diabetic ketoacidosis C: Appendicitis D: Peptic ulcer

Conjunctival injection is commonly seen in:

A: Opioid intoxication B: Alcohol intoxication C: Cannabis intoxication D: Barbiturate intoxication

Cannabinoid hyperemesis syndrome is characterized by:

A: Severe diarrhoea B: Cyclical vomiting relieved by hot showers C: Severe constipation D: Haematemesis

The primary goal of naloxone administration is to:

A: Make the patient fully alert B: Induce vomiting C: Restore breathing D: Prevent withdrawal

The first priority in the approach to intoxication management is:

A: Psychiatric evaluation B: Airway management C: Referral to de-addiction centre D: Family counselling

A 45-year-old man is brought to the emergency department with slurred speech, unsteady gait, and vomiting after heavy alcohol intake. …

A: Emotional lability B: Hyperglycaemia C: Airway compromise D: Poor coordination

A chronic alcohol user presents with withdrawal and confusion. Which intervention is specifically intended to prevent a serious neurological complication?

A: IV fluids alone B: Low-dose antipsychotics C: Thiamine administration D: Activated charcoal

A patient undergoing alcohol withdrawal requires the closest monitoring during which period due to risk of seizures and delirium tremens?

A: Within 6–8 hours B: Within 2–3 days C: Day 5–7 D: After 2 weeks

A patient with hepatic dysfunction is admitted for alcohol withdrawal. Which medication is to be preferred for management?

A: Lorazepam B: Diazepam C: Chlordiazepoxide D: Any of the above

A 28-year-old man is found unconscious with shallow breathing and pinpoint pupils. Which substance intoxication is most likely?

A: Alcohol B: Cannabis C: Nicotine D: Opioids

A known opioid-dependent patient presents with overdose. How should naloxone be initiated in this patient?

A: 0.04–0.1 mg IV B: 10 mg IV bolus C: 2 mg IM immediately D: Oral naloxone

Which medication is most preferred for treating opioid withdrawal?

A: Methadone B: Buprenorphine C: Naloxone D: Naltrexone

A 24-year-old man reports irritability, anxiety, insomnia, vivid dreams, and tremors starting 36 hours after stopping chronic use of cannabis. …

A: It is usually severe with medical complications B: It is typically mild with no medical complications C: Antipsychotics are preferred D: Long-term sedatives are recommended

A patient reports recurrent episodes of severe vomiting relieved temporarily by hot showers. This presentation could be suggestive of:

A: Acute gastroenteritis B: Alcohol withdrawal C: Opioid withdrawal D: Cannabinoid hyperemesis syndrome

A patient planning smoking cessation is started on varenicline. According to recommended practice, it should be initiated:

A: At least 1 week before the quit date B: On the quit date C: After stopping nicotine completely D: Only after nicotine patch failure

Alcohol withdrawal typically begins within:

A: 1–2 hours B: 6–8 hours C: 24–48 hours D: 3–5 days

The first-line drugs for alcohol withdrawal are:

A: Antipsychotics B: Antidepressants C: Benzodiazepines D: Beta blockers

Long-acting benzodiazepines preferred in alcohol withdrawal include:

A: Lorazepam B: Oxazepam C: Chlordiazepoxide D: Midazolam

In alcohol withdrawal, thiamine should be given:

A: After glucose B: Along with insulin C: Before glucose D: Only if seizures occur

Opioid withdrawal usually peaks within:

A: 6–12 hours B: 12–24 hours C: 2–4 days D: 7–10 days

Preferred pharmacological agent for opioid withdrawal is:

A: Methadone B: Buprenorphine C: Naloxone D: Diazepam

Clonidine dose used in opioid withdrawal is:

A: 0.1–0.2 mg every 4 hours B: 5 mg once daily C: 10 mg IV stat D: 1 mg/kg

Cannabis withdrawal typically begins within:

A: 1–2 hours B: 6–8 hours C: 24–48 hours D: 5–7 days

Cannabis withdrawal is generally:

A: Life-threatening B: Severe with complications C: Mild and self-limiting D: Associated with seizures

Nicotine withdrawal peaks within:

A: 4–6 hours B: 2–3 days C: 1 week D: 2 months

The backbone of India’s legal framework for drug control is:

A: Drugs and Cosmetics Act B: Indian Penal Code C: NDPS Act, 1985 D: Mental Healthcare Act

Under the NDPS Act, possession of drugs is punished based on:

A: Age of the offender B: Intention C: Quantity involved D: Type of institution

Which ethical principle is violated when a doctor under influence harms a patient?

A: Autonomy B: Beneficence C: Non-maleficence D: Justice

Reporting an intoxicated colleague is ethically justified primarily to protect:

A: Hospital reputation B: Legal safety C: Patient safety D: Personal image

Abuse of professional privilege leading to enhanced punishment under NDPS Act is covered under:

A: Section 8 B: Section 21 C: Section 32B D: Section 64A

Which of the following is a professional consequence of drug abuse in medical students?

A: Promotion B: Expulsion or suspension C: Increased confidence D: Improved academic performance

Ethical concern in research involving drug abusers mainly relates to:

A: Sample size B: Randomization C: Informed consent D: Publication bias

Doctors abusing drugs are ethically unacceptable mainly because they:

A: Break hospital rules B: Violate ethical principles C: Damage infrastructure D: Reduce workload

Which ethical pillar ensures fairness and equality in patient care?

A: Autonomy B: Beneficence C: Justice D: Confidentiality

.Personal consumption of narcotic drugs is punishable under NDPS Act section

A: Section 8 B: Section 21 C: Section 25 D: Section 27

Which group is most vulnerable to drug abuse?

A: Elderly B: Children C: Students and youth D: Professionals

A common cause of drug abuse among students is:

A: Social pressure B: Peer pressure C: School dropouts D: Family pressure

Drug abuse mainly affects:

A: Physical health only B: Mental health only C: Social life only D: Physical, mental, and social health

Which is an early sign of drug abuse?

A: Improved concentration B: Better attendance C: Sudden behavior changes D: Increased academic performance

Students can prevent drug abuse by:

A: Good social environment B: Healthy family relationship C: Spreading awareness D: Avoiding peers

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