KVV E-Modules

Peptic ulcer disease (PUD) differs from gastritis and erosions because

A: PUD is caused only by H. pylori B: PUD extends deeper into the muscularis mucosa C: PUD is limited to the stomach only D: PUD never involves acid and pepsin

The most common causative factors for PUD include:

A: H. pylori, NSAIDs, and stress-related mucosal damage B: Viral infections, alcohol, and trauma C: Gallstones, obesity, and smoking D: Parasites, fungal infection, and caffeine

Which of the following increases the risk of ulcer formation by decreasing prostaglandin synthesis?

A: Smoking B: NSAIDs C: H. pylori D: Coffee

H. pylori contributes to peptic ulcer formation by all EXCEPT:

A: Increasing gastrin levels and acid secretion B: Direct mucosal injury C: Stimulating immune and inflammatory responses D: Inhibiting acid secretion completely

Typical pain in duodenal ulcer (DU):

A: Occurs immediately after meals B: Occurs 1–3 hours after meals and is relieved by food C: Worsens with food intake D: Never occurs at night

Typical pain in gastric ulcer (GU):

A: Improves with food intake B: Occurs mostly in the morning C: Worsens or precipitates with food intake D: Is never associated with nausea

Which of the following is the first-line pharmacotherapy for H. pylori eradication?

A: PPI + H2RA + sucralfate B: PPI + bismuth + metronidazole + tetracycline C: PPI + clarithromycin + amoxicillin (extended) D: Antacids and dietary changes

Which of the following is TRUE about NSAID-induced ulcers?

A: They are treated effectively without stopping the NSAID B: They result from direct irritation and inhibition of COX-1 enzyme C: They are always painless D: They cannot be treated with PPIs

Why is eradication therapy preferred over conventional antiulcer therapy alone?

A: It provides faster symptom relief B: It reduces recurrence and complications C: It avoids the need for antibiotics D: It eliminates acid production completely