KVV E-Modules

1. FTIR spectroscopy helps in detecting drug–excipient interaction by identifying changes in:

A: Particle size B: Crystalline structure C: Functional group peaks D: Tablet hardness

2. Moisture-mediated degradation in solid dosage forms is mainly accelerated by:

A: Low humidity B. Desiccants C. High temperature and humidity D. Film coating B: Desiccants C: High temperature and humidity D: Film coating

3.Which analytical technique is commonly used to detect drug–excipient incompatibility during preformulation ?

A: Titrimetry B: Thin-layer chromatography C: Differential Scanning Calorimetry (DSC) D: Kjeldahl method

4.Interaction between magnesium stearate and acidic drugs may result in:

A: Increased solubility B: Salt formation C: Polymerization D: Racemization

5.Which of the following is the most common chemical interaction between a primary amine drug and lactose?

A: Oxidation B: Esterification C: Maillard reaction D: Hydrolysis