Quadrant -I (Video)
Weighing and Measuring Techniques
pH Measurement and Buffer Preparation
API Identification and Purity Tests
Quadrant - II (Study Material)
1. Lab equipments manual
2. Fundamentals of pH
3. Active Pharmaceutical Ingredient (API)
Quadrant - III (Assignments)
1. Assignment on Weighing and Measuring Techniques
Q1. Describe the procedure for performing accurate weighing and volume measurement in a laboratory setting. Highlight the types of equipment used, common sources of error and best practices to ensure precision and accuracy. Instructions: • Support your answer with diagrams where applicable. • Include at least one example for both weighing and volume measurement. • Word Limit: 300–500 words.
2. Assignment on pH Measurement and Buffer Preparation
Q2. Explain the procedure for preparing a buffer solution of known concentration. Determine its pH using appropriate theoretical calculations and experimental methods. Discuss the role of each component in maintaining the pH and the factors affecting buffer capacity. Instructions: • Choose any one buffer system (e.g., Acetic acid/Acetate, Ammonia/Ammonium chloride, etc.). • Show all relevant calculations using the Henderson-Hasselbalch equation. • Mention the equipment and reagents required. • Include a step-by-step experimental procedure for pH measurement. • Word Limit: 400–600 words.
3. Assignment on API Identification and Purity Tests
Q1. Describe the methods used for the identification and purity checking of an Active Pharmaceutical Ingredient (API). Discuss both chemical and instrumental techniques, highlighting the principles, procedures, and significance of each. Instructions: • Mention at least two identification techniques (e.g., IR spectroscopy, melting point determination, TLC). • Describe purity assessment methods (e.g., HPLC, titration, loss on drying, residue on ignition). • Include the role of pharmacopoeial standards (e.g., IP, USP) in API quality control. • Support your answer with examples where appropriate. • Word Limit: 500–700 words.